Phobio can't restrain his anger toward Milim. He finds himself faced with Footman and Tear, two masked members of the Moderate Harlequin Alliance, who suggest that he become a Demon Lord to take revenge on Milim. They tell him that he can accomplish this using the power of Charybdis. Meanwhile, the Jura Tempest Federation sends Youm out on a journey to make the world believe he was the champion who defeated the Orc Lord.

The Demon Lord Carrion has sent one of his Three Beastketeers, Phobio, on a raid of Rimuru's city. However, Phobio is quickly defeated when Milim meets his attack with her own. Rimuru and his subordinates then ask Phobio why he has come to their town.

The Jura Tempest Federation, with Rimuru as its leader, has formed an alliance with the Armed Nation of Dwargon. Just as Rimuru thinks there are only peaceful days ahead, he senses an enormous mass of magical power heading straight for his location at an incredible speed. When the smoke from its collision with the ground clears, standing in its place is a humanoid figure. She is the Demon Mord Milim, the one and only Dragonoid and the one bearing the nickname "Destroyer." Ranga, Benimaru, and the others who face her are quickly overwhelmed by her power.

Subaru awakens in front of the fruit stand in Lugunica's capital yet again. Realizing that he's in a hopeless situation, he desperately seeks help from Crusch, Priscilla, and Anastasia, but his limited time continues to tick away... A mysterious figure appears before Subaru and his traveling companions. As the looming beast attacks with a deafening bellow amidst the darkness and fog, Rem determines that it will be too difficult to escape...

I just wanted to protect her. That feeling wasn't a lie. Where did I go wrong?" Rejected by the one who meant more to him than anything, Subaru is still unable to recognize that he may have done something irreversible. He then finds out that some disturbing movement has been detected within Roswaal's domain, where Emilia and the others are. He's certain that he can save them somehow, so in spite of Rem and Crusch's opposition, Subaru makes his way back to Emilia... Upon returning to Roswaal's mansion, Subaru is greeted by an unbelievable sight and wails that this was not what he wanted to happen. Stricken with despair, everything before Subaru starts to go white as, finally, he hears a voice: "You were too late."

At the order of the council of elders that manages Lugunica in the king's absence, Wilhelm and Felis visit Roswaal's mansion as emissaries. Emilia is required in the imperial capital right away, so Subaru asks her to take him along. Emilia tells him this won't be a pleasure trip, but a push from Rem and Roswaal ends in her agreement, so Emilia and Subaru head to the capital. Now all of the candidates to be Lugunica's next king are gathered, and the royal selection is underway. As Emilia joins Priscilla, Crusch, and Anastasia in a meeting of the royal selection participants, Reinhard enters the hall with Felt. According to a new prophecy seen on the Dragon Stone, there are five priestesses with the potential to be the kingdom's next ruler. Reinhard announces that Felt is the fifth priestess, meaning it's time to formally begin the royal selection, but Felt refuses to have any part in it.

Vegapunk Shaka shares with Robin and the others his theory about an ancient kingdom and the 100-Year Void. He even says that he visited Ohara after its destruction. Meanwhile, Luffy and Chopper try to activate the giant robot and something surprising happens.

Nami and the others are attacked by a Pacifista who resembles Jimbei and while they’re in battle, some of Vegapunk’s Satellites look on with excitement. Meanwhile, Luffy and the others find something extraordinary at the scrap heap.

The Straw Hats without Luffy, Chopper, and Jimbei are taken to the laboratory on the clouds far above the ground by Lilith. They get excited about the things they've never seen before. However, inside the laboratory, a new threat is waiting for them.

The Blackbeard Pirates ambushed the Heart Pirates led by Law. The Blackbeard Pirates’ top officers use a variety of formidable Devil Fruit powers and keep pushing the Heart Pirates in order to obtain the copies of the Road Ponegliffs.

While Luffy and the others are enjoying the futuristic machines of Egghead, someone who resembles Bartholomew Kuma comes after them. When Luffy tries to fight back, Bonney stops him and reveals her shocking relationship with Kuma.

A young girl who came out of the big robot names herself Dr. Vegapunk and it surprises Franky and the rest of the Straw Hats. Meanwhile, Luffy’s group gets to the surface of the island where futuristic buildings stand and unknown giant creatures wander about.

Luffy and Chopper fall into the rough cold sea along with the mysterious girl. Jimbei tries to help them but another attack comes from the unknown creature. Meanwhile, the Sunny is hit by torpedoes and the rest of the Straw Hats are thrown into the sea, too.

Sabo, the Chief of Staff of the Revolutionary Army, contacts Koala and everyone in Kamabakka Queendom. He explains to them about the things that he is accused of, but someone who was eavesdropping on the call takes a stunning action.

The three-way struggle between the Navy, the Blackbeard Pirates, and the Kuja Pirates comes to an end when an unexpected figure shows up. On the Sunny, the Straw Hats talk about the recent incidents around the world and Luffy’s words surprise everyone.

Navy Captain Koby comes to the Island of Women to arrest Pirate Empress Hancock with the new Pacifistas. While the Navy and Kuja fighters clash, Blackbeard comes to raid, also targeting　Hancock.

Luffy and the other Straw Hats’ new bounties are revealed. Meanwhile, at Emptee Bluffs Island,　Crocodile and the greatest swordsman in the world Mihawk, visit Buggy to discuss their newly-established organization, Cross Guild.

Momonosuke, Kin’emon, and Yamato look back on the Land of Wano after Kaido and Orochi were taken down. They talk about the things that happened in the country after the raid on Onigashima and how Momonosuke worked hard to become a great Shogun.

Chopper and Bepo look back on Trafalgar Law’s life. They explain how he met Luffy, formed an alliance, and traveled to Punk Hazard, Dressrosa, and the Land of Wano to take down the Emperors of the Sea.

The team visits the famous World Tree, a place of peace and nature... or so it should be. Instead they find a depraved den of Other Worlders, a righteous "hero", and a mysterious dancer. Worst of all, Sensei is missing something VERY important.